Does TapenTadol Cause Addiction if used for long term?
Added: (Thu Apr 11 2019)
Pressbox (Press Release) -
TapenTadol is a novel synthetic painkiller or analgesic drug with the dual action of MOR and NRI. MOR or mu–opioid receptor agonistic action results pain relief whereas the NRI i.e. Nor-epinephrine Reuptake Inhibitor brings relief of chronic neuropathic pain.
The absorption of the drug is quite rapid. The mean maximal concentration of serum reaches at 1.25 -1.5hr after in taking orally. The conjugated metabolites released after glucuronidation is rapidly excreted via the kidney almost entirely. But the concomitant administration of TapenTadol with other CNS (central nervous system) depressants like sedatives, tranquilizer, other opioids, and alcohol may lead to TapenTadol Addiction.
After USFDA approval, TapenTadol doses are available in 50, 75 or 100 mg of the instant release (IR) tablets whereas the extended-release tablets (ER) are available in 50,100,150, 200 and also 250 mg tablets.
As the drug primarily helps to slow down the pain in post-operative patients it might as well be used for drug abuse. TapenTadol usually stays in the body for about 22 hours depending on other factors like age, metabolic rate, health conditions tolerance and dosage. TapenTadol long term usage may also be one of the factors. FDA or Food and Drug Acts, have labeled TapenTadol as a Schedule II drug under the category of “Controlled Substance Act” in 2009. This types of drugs have a large probability of beings used for physical and psychological addiction and misuse. As it is used for short-term relaxation from pain its effect is prominent after a minimum of 30 minutes after intake. In USA TapenTadol abuse by college students by chewing, swallowing even inhalation was reported.
The chief concerns with TapenTadol Addiction are withdrawal, seeking behavior, abuse, and physical dependence. The drugs can be detected in drug screening tests. IT can found in urine for 3 to 4 days and but will not be found in the blood after 24hrs. But it stays on the hair not more than 90 after last administration.
However, TapenTadol seems to have a lower abuse risk than other prevalent opioids as it has a low affinity for its MOR actions. Studies show that in comparison to other opioid addiction like oxycodone, TapenTadol Addiction is at much lower risk as found by abuse diagnosis, which makes it the preferred drug of use. TapenTadol long term usage mostly causes drowsiness, nausea, liver problems and fatigue.
Though more studies regarding the long term safety of TapenTadol should be conducted, but till now the additive the behavior seems to be quite uncertain. With the bulk demand of the drug, TapenTadol COD services can be availed by various online service providers as well as pharmaceutical applications.
For patients, reputed online pharmacies provide easy TapenTadol COD services as it is difficult for patients with such medication to actually procure the medicines from a local pharmacy. Moreover, the COD options also secure the patient the timely delivery as well as proper identification of the medicines without the risk of fraudulent online practices.
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