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An War vs Sorafenib And How To Winning It

Added: (Fri Aug 11 2017)

Pressbox (Press Release) - The mean age of our study population was 62.1 years (range 11-100), 47% were male, and the average BMI was 28.4 �� 7.5. Of those with DVT, the mean age was 61.8 years (range 11-92), 42.5% were male, and average BMI was 26.1 �� 5.7. None of the recorded comorbidities, pathologies, or interventions was significantly associated with DVT except for BMI, craniotomy, and chemoprophylaxis (Table II). DVT occurred in five of 55 patients with BMI>30 (9.1%) vs 35 of 119 patients with BMI <30 (29.4%, P = .01). This increased risk for patients with BMI <30 is independent of the presence of malignancy or of the length of hospital stay. Thirty-seven percent of patient status post craniotomy vs 19% oxyclozanide of patients without craniotomy developed DVT. This association was not affected by chemoprophylaxis use as an equivalent percentage of patients without chemoprophylaxis (41%) compared with the overall cohort (50%) developed DVT. Chemical prophylaxis was provided Sorafenib cost for 145 (83.3%) patients. The majority of these patients were given 5000 units of unfractionated heparin either two or three times daily. Two patients were given once daily enoxaparin. DVT developed in 19.3% (28/145) of patients receiving chemoprophylaxis and 41.4% (12/29) receiving no chemical prophylaxis (P <.01). Of the isolated calf DVTs, three patients did not receive any treatment, five were maintained on prophylactic doses of anticoagulation with twice daily UFH, five were treated with therapeutic anticoagulation (LMWH in one, warfarin in three, intravenous heparin in one), and four were treated with IVCF. The characteristics of our isolated calf DVT cohort can be seen in Table III. Twelve of the HIF cancer 17 patients with isolated calf DVT had follow-up studies performed. Three of these patients had bilateral calf DVTs, therefore totaling 15 calf DVTs with follow-up in this study group. Of these 15 limbs with isolated calf DVT, 8 persisted without propagation during mean follow-up of 17 days, 4 resolved (1 patient was treated with therapeutic LMWH, 1 with warfarin, 1 with prophylactic UFH, and 1 was untreated) over a mean follow-up of 26 days, and 2 (13.3%) progressed proximally (one gastrocnemius thrombus to the popliteal vein (POP), one soleal thrombus to the ileofemoral vein) by 8 and 11 days of follow-up, respectively. Of the two patients with propagation, one (POP) was treated with warfarin and one (ileofemoral) underwent thrombectomy and IVCF placement in addition to receiving warfarin therapy. In comparing calf muscle vein propagation rates with tibial vein propagation rates, there was no statistical significance between the two groups (P = .3). Of the 5 patients without follow-up studies, 2 had IVCF placed, 1 was treated with prophylactic UFH, 1 received warfarin therapy, and 1 was not treated at all. No patients developed PE in this study.

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